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In Hepatic Fibrosis, Liver Sinusoidal Endothelial Cells Acquire Enhanced Immunogenicity

The normal liver is characterized by immunologic tolerance. Primary mediators of hepatic immune tolerance are liver sinusoidal endothelial cells (LSECs). LSECs block adaptive immunogenic responses to Ag and induce the generation of T regulatory cells. Hepatic fibrosis is characterized by both intens...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Connolly, Michael K., Bedrosian, Andrea S., Malhotra, Ashim, Henning, Justin R., Ibrahim, Junaid, Vera, Valery, Cieza-Rubio, Napoleon E., Hassan, Burhan U., Pachter, H. Leon, Cohen, Steven, Frey, Alan B., Miller, George
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2010
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3119346/
https://ncbi.nlm.nih.gov/pubmed/20639479
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1000332
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