Dendritic Cell Depletion Exacerbates Acetaminophen Hepatotoxicity

Acetaminophen (APAP) overdose is one of the most frequent causes of acute liver failure in the United States and is primarily mediated by toxic metabolites which accumulate in the liver upon depletion of glutathione stores. However, cells of the innate immune system, including NK cells, neutrophils,...

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Auteurs principaux: Connolly, Michael K., Ayo, Diego, Malhotra, Ashim, Hackman, Michael, Bedrosian, Andrea S., Ibrahim, Junaid, Cieza-Rubio, Napoleon E., Nguyen, Andrew H., Henning, Justin R., Dorvil-Castro, Monica, Pachter, H. Leon, Miller, George
Format: Artigo
Langue:Inglês
Publié: 2011
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3166555/
https://ncbi.nlm.nih.gov/pubmed/21574173
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.24429
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