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Dendritic Cell Depletion Exacerbates Acetaminophen Hepatotoxicity
Acetaminophen (APAP) overdose is one of the most frequent causes of acute liver failure in the United States and is primarily mediated by toxic metabolites which accumulate in the liver upon depletion of glutathione stores. However, cells of the innate immune system, including NK cells, neutrophils,...
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| Hauptverfasser: | , , , , , , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2011
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3166555/ https://ncbi.nlm.nih.gov/pubmed/21574173 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.24429 |
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