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Insights into prion biology: Integrating a protein misfolding pathway with its cellular environment
Protein misfolding and assembly into ordered, self-templating aggregates (amyloid) has emerged as a novel mechanism for regulating protein function. For a subclass of amyloidogenic proteins known as prions, this process induces transmissible changes in normal cellular physiology, ranging from neurod...
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| Main Authors: | , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
Landes Bioscience
2011
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3166505/ https://ncbi.nlm.nih.gov/pubmed/21654204 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/pri.5.2.16413 |
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