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Insights into prion biology: Integrating a protein misfolding pathway with its cellular environment

Protein misfolding and assembly into ordered, self-templating aggregates (amyloid) has emerged as a novel mechanism for regulating protein function. For a subclass of amyloidogenic proteins known as prions, this process induces transmissible changes in normal cellular physiology, ranging from neurod...

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Detalhes bibliográficos
Main Authors: DiSalvo, Susanne, Serio, Tricia R
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3166505/
https://ncbi.nlm.nih.gov/pubmed/21654204
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/pri.5.2.16413
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