Prior exposure to glucocorticoids potentiates lipopolysaccharide induced mechanical allodynia and spinal neuroinflammation

While stress and stress-induced glucocorticoids are classically considered immunosuppressive, they can also enhance proinflammatory responses to subsequent challenges. Corticosterone (CORT) primes rat immune cells, exacerbating pro-inflammatory responses to subsequent immune challenges. Stress can a...

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Autori principali: Loram, Lisa C, Taylor, Frederick R, Strand, Keith A, Frank, Matthew G, Sholar, Paige, Harrison, Jacqueline A, Maier, Steven F, Watkins, Linda R
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2011
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3166396/
https://ncbi.nlm.nih.gov/pubmed/21536123
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbi.2011.04.013
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