PRIOR LAPAROTOMY OR CORTICOSTERONE POTENTIATES LIPOPOLYSACCHARIDE-INDUCED FEVER AND SICKNESS BEHAVIORS

Stimulating sensitized immune cells with a subsequent immune challenge results in potentiated pro-inflammatory responses translating into exacerbated sickness responses (i.e. fever, pain and lethargy). Both corticosterone (CORT) and laparotomy cause sensitization, leading to enhanced sickness-induce...

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Detalhes bibliográficos
Main Authors: Hains, Leah E., Loram, Lisa C., Taylor, Frederick R, Strand, Keith A, Wieseler, Julie L., Barrientos, Ruth M., Young, Jennifer J., Frank, Matthew G, Sobesky, Julia, Martin, Thomas J., Eisenach, James C., Maier, Steven F., Johnson, John D., Fleshner, Monika, Watkins, Linda R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3205218/
https://ncbi.nlm.nih.gov/pubmed/21907418
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jneuroim.2011.08.011
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