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PRIOR LAPAROTOMY OR CORTICOSTERONE POTENTIATES LIPOPOLYSACCHARIDE-INDUCED FEVER AND SICKNESS BEHAVIORS

Stimulating sensitized immune cells with a subsequent immune challenge results in potentiated pro-inflammatory responses translating into exacerbated sickness responses (i.e. fever, pain and lethargy). Both corticosterone (CORT) and laparotomy cause sensitization, leading to enhanced sickness-induce...

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Dettagli Bibliografici
Autori principali: Hains, Leah E., Loram, Lisa C., Taylor, Frederick R, Strand, Keith A, Wieseler, Julie L., Barrientos, Ruth M., Young, Jennifer J., Frank, Matthew G, Sobesky, Julia, Martin, Thomas J., Eisenach, James C., Maier, Steven F., Johnson, John D., Fleshner, Monika, Watkins, Linda R.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3205218/
https://ncbi.nlm.nih.gov/pubmed/21907418
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jneuroim.2011.08.011
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