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Pyk2 is a downstream mediator of the IL-2 receptor-coupled Jak signaling pathway

Many cytokines transmit signals to the cell interior through activation of receptor-associated, Janus family protein tyrosine kinases (Jak PTKs). The interleukin-2 receptor (IL-2R) is associated with the Jak1 and Jak3 PTKs, and ligand-induced activation of these PTKs is essential for lymphocyte prol...

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Detalhes bibliográficos
Main Authors: Miyazaki, Tadaaki, Takaoka, Akinori, Nogueira, Leonor, Dikic, Ivan, Fujii, Hodaka, Tsujino, Shiho, Mitani, Yukiko, Maeda, Michiyuki, Schlessinger, Joseph, Taniguchi, Tadatsugu
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 1998
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC316631/
https://ncbi.nlm.nih.gov/pubmed/9512511
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