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Differential requirement of the cytoplasmic subregions of γc chain in T cell development and function

The common cytokine receptor γ chain (γc), a shared component of the receptors for IL-2, IL-4, IL-7, IL-9, and IL-15, is critical for the development and function of lymphocytes. The cytoplasmic domain of γc consists of 85 aa, in which the carboxyl-terminal 48 aa are essential for its interaction wi...

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Detalhes bibliográficos
Main Authors: Tsujino, Shiho, Di Santo, James P., Takaoka, Akinori, McKernan, Teresa L., Noguchi, Shigeru, Taya, Choji, Yonekawa, Hiromichi, Saito, Takashi, Taniguchi, Tadatsugu, Fujii, Hodaka
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 2000
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC27056/
https://ncbi.nlm.nih.gov/pubmed/10962026
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