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Novel Basophil- or Eosinophil-Depleted Mouse Models for Functional Analyses of Allergic Inflammation

Basophils and eosinophils play important roles in various host defense mechanisms but also act as harmful effectors in allergic disorders. We generated novel basophil- and eosinophil-depletion mouse models by introducing the human diphtheria toxin (DT) receptor gene under the control of the mouse CD...

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Библиографические подробности
Главные авторы: Matsuoka, Kunie, Shitara, Hiroshi, Taya, Choji, Kohno, Kenji, Kikkawa, Yoshiaki, Yonekawa, Hiromichi
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2013
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3620047/
https://ncbi.nlm.nih.gov/pubmed/23577180
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0060958
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