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Novel Basophil- or Eosinophil-Depleted Mouse Models for Functional Analyses of Allergic Inflammation

Basophils and eosinophils play important roles in various host defense mechanisms but also act as harmful effectors in allergic disorders. We generated novel basophil- and eosinophil-depletion mouse models by introducing the human diphtheria toxin (DT) receptor gene under the control of the mouse CD...

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Detalhes bibliográficos
Principais autores: Matsuoka, Kunie, Shitara, Hiroshi, Taya, Choji, Kohno, Kenji, Kikkawa, Yoshiaki, Yonekawa, Hiromichi
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3620047/
https://ncbi.nlm.nih.gov/pubmed/23577180
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0060958
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