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Novel Basophil- or Eosinophil-Depleted Mouse Models for Functional Analyses of Allergic Inflammation

Basophils and eosinophils play important roles in various host defense mechanisms but also act as harmful effectors in allergic disorders. We generated novel basophil- and eosinophil-depletion mouse models by introducing the human diphtheria toxin (DT) receptor gene under the control of the mouse CD...

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Autors principals: Matsuoka, Kunie, Shitara, Hiroshi, Taya, Choji, Kohno, Kenji, Kikkawa, Yoshiaki, Yonekawa, Hiromichi
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2013
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3620047/
https://ncbi.nlm.nih.gov/pubmed/23577180
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0060958
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