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Lack of nuclear translocation of cytoplasmic domains of IL-2/IL-15 receptor subunits

Some sensors of extracellular signaling molecules such as Notch and sterol response element binding protein (SREBP) receive ligand-induced intra-membrane proteolysis followed by nuclear translocation of their cytoplasmic domains to regulate gene expression programs in the nucleus. It has not been ex...

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Detalhes bibliográficos
Main Authors: Fujii, Hodaka, Hoshino, Akemi
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2693279/
https://ncbi.nlm.nih.gov/pubmed/19329337
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cyto.2009.02.014
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