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Tree-Based Position Weight Matrix Approach to Model Transcription Factor Binding Site Profiles

Most of the position weight matrix (PWM) based bioinformatics methods developed to predict transcription factor binding sites (TFBS) assume each nucleotide in the sequence motif contributes independently to the interaction between protein and DNA sequence, usually producing high false positive predi...

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Detalhes bibliográficos
Main Authors: Bi, Yingtao, Kim, Hyunsoo, Gupta, Ravi, Davuluri, Ramana V.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3166302/
https://ncbi.nlm.nih.gov/pubmed/21912677
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0024210
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