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IsoformEx: isoform level gene expression estimation using weighted non-negative least squares from mRNA-Seq data

BACKGROUND: mRNA-Seq technology has revolutionized the field of transcriptomics for identification and quantification of gene transcripts not only at gene level but also at isoform level. Estimating the expression levels of transcript isoforms from mRNA-Seq data is a challenging problem due to the p...

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Bibliographische Detailangaben
Hauptverfasser: Kim, Hyunsoo, Bi, Yingtao, Pal, Sharmistha, Gupta, Ravi, Davuluri, Ramana V
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3180389/
https://ncbi.nlm.nih.gov/pubmed/21794104
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-12-305
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