Inhibition of aldose reductase prevents colon cancer metastasis

Colon cancer is the third most common cause of cancer and is the second leading cause of cancer deaths in the USA. Although inhibition of aldose reductase (AR) is known to prevent human colon cancer cell growth in nude mice xenografts, the role of AR in the regulation of cancer metastasis is not kno...

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Main Authors: Tammali, Ravinder, Reddy, Aramati B.M., Saxena, Ashish, Rychahou, Piotr G., Evers, B. Mark, Qiu, Suimin, Awasthi, Sanjay, Ramana, Kota V., Srivastava, Satish K.
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2011
Teme:
Cancer Prevention
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3166198/
https://ncbi.nlm.nih.gov/pubmed/21642355
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgr102
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