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Aldose reductase deficiency in mice prevents azoxymethane-induced colonic preneoplastic aberrant crypt foci formation

Aldose reductase (AR; EC 1.1.1.21), an nicotinamide adenine dinucleotide phosphate-dependent aldo–keto reductase, has been shown to be involved in oxidative stress signaling initiated by inflammatory cytokines, chemokines and growth factors. Recently, we have shown that inhibition of this enzyme pre...

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Detalhes bibliográficos
Main Authors: Tammali, Ravinder, Reddy, Aramati B. M., Ramana, Kota V., Petrash, J. Mark, Srivastava, Satish K.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2722145/
https://ncbi.nlm.nih.gov/pubmed/19028703
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgn246
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