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Inhibition of Aldose Reductase Prevents Angiogenesis in vitro and in vivo

We have recently shown that aldose reductase (AR, EC 1.1.1.21) a nicotinamide adenine dinucleotide phosphate-dependent aldo-keto reductase, known to be involved in oxidative stress-signaling, prevents human colon cancer cell growth in culture as well as in nude mice xenografts. Inhibition of AR also...

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Bibliographic Details
Main Authors: Tammali, Ravinder, Reddy, Aramati B. M., Srivastava, Satish K., Ramana, Kota V.
Format: Artigo
Language:Inglês
Published: 2011
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3103619/
https://ncbi.nlm.nih.gov/pubmed/21409599
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10456-011-9206-4
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