Genome-Wide Functional Profiling Reveals Genes Required for Tolerance to Benzene Metabolites in Yeast

Benzene is a ubiquitous environmental contaminant and is widely used in industry. Exposure to benzene causes a number of serious health problems, including blood disorders and leukemia. Benzene undergoes complex metabolism in humans, making mechanistic determination of benzene toxicity difficult. We...

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Detalhes bibliográficos
Main Authors: North, Matthew, Tandon, Vickram J., Thomas, Reuben, Loguinov, Alex, Gerlovina, Inna, Hubbard, Alan E., Zhang, Luoping, Smith, Martyn T., Vulpe, Chris D.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3166172/
https://ncbi.nlm.nih.gov/pubmed/21912624
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0024205
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