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Vaccine Platforms Combining Circumsporozoite Protein and Potent Immune Modulators, rEA or EAT-2, Paradoxically Result in Opposing Immune Responses

BACKGROUND: Malaria greatly impacts the health and wellbeing of over half of the world's population. Promising malaria vaccine candidates have attempted to induce adaptive immune responses to Circumsporozoite (CS) protein. Despite the inclusion of potent adjuvants, these vaccines have limited p...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Schuldt, Nathaniel J., Aldhamen, Yasser A., Appledorn, Daniel M., Seregin, Sergey S., Kousa, Youssef, Godbehere, Sarah, Amalfitano, Andrea
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Public Library of Science 2011
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3166157/
https://ncbi.nlm.nih.gov/pubmed/21912619
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0024147
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