Sirolimus demonstrates activity in the primary therapy of acute graft-versus-host disease without systemic glucocorticoids

BACKGROUND: Advances in acute graft-versus-host disease therapy are needed. DESIGN AND METHODS: We examined the efficacy of sirolimus as primary therapy for acute graft-versus-host disease in 32 patients. RESULTS: Acute graft-versus-host disease involved the skin in 53% of cases, gastrointestinal tr...

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Autors principals: Pidala, Joseph, Tomblyn, Marcie, Nishihori, Taiga, Field, Teresa, Ayala, Ernesto, Perkins, Janelle, Fernandez, Hugo, Locke, Fred, Perez, Lia, Ochoa, Jose Leonel, Alsina, Melissa, Anasetti, Claudio
Format: Artigo
Idioma:Inglês
Publicat: Ferrata Storti Foundation 2011
Matèries:
Original Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3166106/
https://ncbi.nlm.nih.gov/pubmed/21565902
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2011.041236
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