P-TEFb kinase is required for HIV Tat transcriptional activation in vivo and in vitro
To identify novel inhibitors of transcriptional activation by the HIV Tat protein, we used a combination of in vitro and in vivo Tat-dependent transcription assays to screen >100,000 compounds. All compounds identified blocked Tat-dependent stimulation of transcriptional elongation. Analysis of a pa...
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| Publicat a: | Genes Dev |
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| Autors principals: | , , , , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Cold Spring Harbor Laboratory Press
1997
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC316604/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9334326/ https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gad.11.20.2633 |
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