A model of repression: CTD analogs and PIE-1 inhibit transcriptional elongation by P-TEFb

The positive transcription elongation factor b (P-TEFb) contains cyclin T1 (CycT1) and cyclin-dependent kinase 9 (Cdk9). For activating the expression of eukaryotic genes, the histidine-rich sequence in CycT1 binds the heptapeptide repeats in the C-terminal domain (CTD) of RNA polymerase II (RNAPII)...

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Detalhes bibliográficos

Publicado no:	Genes Dev
Principais autores:	Zhang, Fan, Barboric, Matjaz, Blackwell, T. Keith, Peterlin, B. Matija
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Cold Spring Harbor Laboratory Press 2003
Assuntos:	Research Paper
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC196018/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12651893/ https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gad.1068203
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