A model of repression: CTD analogs and PIE-1 inhibit transcriptional elongation by P-TEFb
The positive transcription elongation factor b (P-TEFb) contains cyclin T1 (CycT1) and cyclin-dependent kinase 9 (Cdk9). For activating the expression of eukaryotic genes, the histidine-rich sequence in CycT1 binds the heptapeptide repeats in the C-terminal domain (CTD) of RNA polymerase II (RNAPII)...
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| Yayımlandı: | Genes Dev |
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| Asıl Yazarlar: | , , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
Cold Spring Harbor Laboratory Press
2003
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC196018/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12651893/ https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gad.1068203 |
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