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Peripheral antinociceptive effects of inhibitors of monoacylglycerol lipase in a rat model of inflammatory pain

BACKGROUND AND PURPOSE: The endocannabinoid 2-arachidonoylglycerol (2-AG) is degraded primarily by monoacylglycerol lipase (MGL). We compared peripheral antinociceptive effects of JZL184, a novel irreversible MGL inhibitor, with the reversible MGL-preferring inhibitor URB602 and exogenous 2-AG in ra...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Guindon, Josée, Guijarro, Ana, Piomelli, Daniele, Hohmann, Andrea G
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Blackwell Publishing Ltd 2011
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3165956/
https://ncbi.nlm.nih.gov/pubmed/21198549
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1476-5381.2010.01192.x
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