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The Role of Amino-Terminal Sequences in Cellular Localization and Antiviral Activity of APOBEC3B

Human APOBEC3B (A3B) has been described as a potent inhibitor of retroviral infection and retrotransposition. However, we found that the predominantly nuclear A3B only weakly restricted infection by HIV-1, HIV-1Δvif, and human T-cell leukemia virus type 1 (HTLV-1), while significantly inhibiting LIN...

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主要な著者: Pak, Vladimir, Heidecker, Gisela, Pathak, Vinay K., Derse, David
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Microbiology 2011
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オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3165795/
https://ncbi.nlm.nih.gov/pubmed/21715505
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02645-10
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