Comparative Study of the Genetic Barriers and Pathways towards Resistance of Selective Inhibitors of Hepatitis C Virus Replication

Hepatitis C virus (HCV) inhibitors include direct-acting antivirals (DAAs) such as NS3 serine protease inhibitors, nucleoside and nonnucleoside polymerase inhibitors, and host-targeting antivirals (HTAs) such as cyclophilin inhibitors that have been developed in recent years. Drug-resistant HCV vari...

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Bibliographic Details
Main Authors: Delang, Leen, Vliegen, Inge, Froeyen, Mathy, Neyts, Johan
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2011
Subjects:
Antiviral Agents
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3165355/
https://ncbi.nlm.nih.gov/pubmed/21709100
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00294-11
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