Phylogenetic Sequence Variations in Bacterial rRNA Affect Species-Specific Susceptibility to Drugs Targeting Protein Synthesis

Antibiotics targeting the bacterial ribosome typically bind to highly conserved rRNA regions with only minor phylogenetic sequence variations. It is unclear whether these sequence variations affect antibiotic susceptibility or resistance development. To address this question, we have investigated th...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Akshay, Subramanian, Bertea, Mihai, Hobbie, Sven N., Oettinghaus, Björn, Shcherbakov, Dimitri, Böttger, Erik C., Akbergenov, Rashid
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2011
Témata:
Mechanisms of Resistance
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3165350/
https://ncbi.nlm.nih.gov/pubmed/21730122
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01398-10
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky