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Mutation K42R in Ribosomal Protein S12 Does Not Affect Susceptibility of Mycobacterium smegmatis 16S rRNA A-Site Mutants to 2-Deoxystreptamines

Recent studies have suggested that ribosomal protein S12 modulates 16S rRNA function and susceptibility to 2-deoxystreptamine aminoglycosides. To study whether the non-restrictive K42R mutation in RpsL affects 2-deoxystreptamine susceptibility in Mycobacterium smegmatis, we studied the drug suscepti...

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Detalhes bibliográficos
Main Authors: Kalapala, Sarath K., Hobbie, Sven N., Böttger, Erik C., Shcherbakov, Dmitry
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2916820/
https://ncbi.nlm.nih.gov/pubmed/20700526
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0011960
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