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Role of 16S rRNA Helix 44 in Ribosomal Resistance to Hygromycin B

Hygromycin B is an aminoglycoside antibiotic active against prokaryotic and eukaryotic ribosomes. Ribosomal alterations in bacteria conferring resistance to hygromycin B have not been described, prompting us to use a single rRNA allelic derivative of the gram-positive bacterium Mycobacterium smegmat...

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Detalhes bibliográficos
Main Authors: Pfister, P., Risch, M., Brodersen, D. E., Böttger, E. C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC153343/
https://ncbi.nlm.nih.gov/pubmed/12709313
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.47.5.1496-1502.2003
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