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Melatonin Attenuates Colistin-Induced Nephrotoxicity in Rats

Colistin-induced nephrotoxicity is a dose-limiting adverse effect when colistin is used against Gram-negative pathogens. This study examined the nephroprotective effect of melatonin against colistin in rats. Rats (n = 7 per group) were treated intravenously twice daily with saline, colistin (at incr...

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Detalhes bibliográficos
Main Authors: Yousef, Jumana M., Chen, Gong, Hill, Prue A., Nation, Roger L., Li, Jian
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3165279/
https://ncbi.nlm.nih.gov/pubmed/21709095
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00328-11
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