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Preliminary Clinical Study of the Effect of Ascorbic Acid on Colistin-Associated Nephrotoxicity

Nephrotoxicity is a dose-limiting factor of colistin, a last-line therapy for multidrug-resistant Gram-negative bacterial infections. An earlier animal study revealed a protective effect of ascorbic acid against colistin-induced nephrotoxicity. The present randomized controlled study was conducted i...

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Publicat a:Antimicrob Agents Chemother
Autors principals: Sirijatuphat, Rujipas, Limmahakhun, Samornrod, Sirivatanauksorn, Vorapan, Nation, Roger L., Li, Jian, Thamlikitkul, Visanu
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2015
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4432219/
https://ncbi.nlm.nih.gov/pubmed/25801556
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00280-15
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