Reversibility of Adverse, Calcineurin-Dependent Cardiac Remodeling

BACKGROUND: Studies to dissect the role of calcineurin in pathological cardiac remodeling have relied heavily on murine models, where genetic gain- and loss-of-function manipulations are initiated at or before birth. However, the great majority of clinical cardiac pathology occurs in adults. Yet, no...

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Hauptverfasser: Berry, Jeff M., Le, Vien, Rotter, David, Battiprolu, Pavan K., Grinsfelder, Bennett, Tannous, Paul, Burchfield, Jana S., Czubryt, Michael, Backs, Johannes, Olson, Eric N., Rothermel, Beverly A., Hill, Joseph A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2011
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3164792/
https://ncbi.nlm.nih.gov/pubmed/21700928
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.110.228452
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