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Rel-dependent induction of A1 transcription is required to protect B cells from antigen receptor ligation-induced apoptosis

In response to different extracellular signals, Rel/NF-κB transcription factors are critical regulators of apoptosis in a variety of cell types. Here we show that in normal B and T cells, expression of the Bcl-2 prosurvival homolog, A1, is rapidly induced in a Rel-dependent manner by mitogens. In B-...

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Bibliografski detalji
Glavni autori: Grumont, Raelene J., Rourke, Ian J., Gerondakis, Steve
Format: Artigo
Jezik:Inglês
Izdano: Cold Spring Harbor Laboratory Press 1999
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC316474/
https://ncbi.nlm.nih.gov/pubmed/10049356
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