Rel-dependent induction of A1 transcription is required to protect B cells from antigen receptor ligation-induced apoptosis
In response to different extracellular signals, Rel/NF-κB transcription factors are critical regulators of apoptosis in a variety of cell types. Here we show that in normal B and T cells, expression of the Bcl-2 prosurvival homolog, A1, is rapidly induced in a Rel-dependent manner by mitogens. In B-...
Sábháilte in:
| Foilsithe in: | Genes Dev |
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| Príomhchruthaitheoirí: | , , |
| Formáid: | Artigo |
| Teanga: | Inglês |
| Foilsithe / Cruthaithe: |
Cold Spring Harbor Laboratory Press
1999
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| Ábhair: | |
| Rochtain ar líne: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC316474/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10049356/ https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gad.13.4.400 |
| Clibeanna: |
Níl clibeanna ann, Bí ar an gcéad duine le clib a chur leis an taifead seo!
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