Rel-dependent induction of A1 transcription is required to protect B cells from antigen receptor ligation-induced apoptosis

In response to different extracellular signals, Rel/NF-κB transcription factors are critical regulators of apoptosis in a variety of cell types. Here we show that in normal B and T cells, expression of the Bcl-2 prosurvival homolog, A1, is rapidly induced in a Rel-dependent manner by mitogens. In B-...

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Bibliografische gegevens

Gepubliceerd in:	Genes Dev
Hoofdauteurs:	Grumont, Raelene J., Rourke, Ian J., Gerondakis, Steve
Formaat:	Artigo
Taal:	Inglês
Gepubliceerd in:	Cold Spring Harbor Laboratory Press 1999
Onderwerpen:	Research Paper
Online toegang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC316474/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10049356/ https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gad.13.4.400
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