Rel-dependent induction of A1 transcription is required to protect B cells from antigen receptor ligation-induced apoptosis
In response to different extracellular signals, Rel/NF-κB transcription factors are critical regulators of apoptosis in a variety of cell types. Here we show that in normal B and T cells, expression of the Bcl-2 prosurvival homolog, A1, is rapidly induced in a Rel-dependent manner by mitogens. In B-...
Uloženo v:
| Vydáno v: | Genes Dev |
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| Hlavní autoři: | , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Cold Spring Harbor Laboratory Press
1999
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC316474/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10049356/ https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gad.13.4.400 |
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