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PERP, an apoptosis-associated target of p53, is a novel member of the PMP-22/gas3 family

The p53 tumor suppressor activates either cell cycle arrest or apoptosis in response to cellular stress. Mouse embryo fibroblasts (MEFs) provide a powerful primary cell system to study both p53-dependent pathways. Specifically, in response to DNA damage, MEFs undergo p53-dependent G(1) arrest, where...

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Bibliographische Detailangaben
Hauptverfasser: Attardi, Laura D., Reczek, Elizabeth E., Cosmas, Corinna, Demicco, Elizabeth G., McCurrach, Mila E., Lowe, Scott W., Jacks, Tyler
Format: Artigo
Sprache:Inglês
Veröffentlicht: Cold Spring Harbor Laboratory Press 2000
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC316461/
https://ncbi.nlm.nih.gov/pubmed/10733530
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