mus304 encodes a novel DNA damage checkpoint protein required during Drosophila development

Checkpoints block cell cycle progression in eukaryotic cells exposed to DNA damaging agents. We show that several Drosophila homologs of checkpoint genes, mei-41, grapes, and 14-3-3ε, regulate a DNA damage checkpoint in the developing eye. We have used this assay to show that the mutagen-sensitive g...

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Detalhes bibliográficos

Publicado no:	Genes Dev
Principais autores:	Brodsky, Michael H., Sekelsky, Jeff J., Tsang, Garson, Hawley, R. Scott, Rubin, Gerald M.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Cold Spring Harbor Laboratory Press 2000
Assuntos:	Research Paper
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC316460/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10733527/
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