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Drosophila unpaired encodes a secreted protein that activates the JAK signaling pathway

In vertebrates, many cytokines and growth factors have been identified as activators of the JAK/STAT signaling pathway. In Drosophila, JAK and STAT molecules have been isolated, but no ligands or receptors capable of activating the pathway have been described. We have characterized the unpaired (upd...

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Bibliografske podrobnosti
izdano v:Genes Dev
Main Authors: Harrison, Douglas A., McCoon, Patricia E., Binari, Richard, Gilman, Michael, Perrimon, Norbert
Format: Artigo
Jezik:Inglês
Izdano: Cold Spring Harbor Laboratory Press 1998
Teme:
Online dostop:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC317220/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9784499/
https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gad.12.20.3252
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