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Drosophila unpaired encodes a secreted protein that activates the JAK signaling pathway

In vertebrates, many cytokines and growth factors have been identified as activators of the JAK/STAT signaling pathway. In Drosophila, JAK and STAT molecules have been isolated, but no ligands or receptors capable of activating the pathway have been described. We have characterized the unpaired (upd...

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Detalles Bibliográficos
Main Authors: Harrison, Douglas A., McCoon, Patricia E., Binari, Richard, Gilman, Michael, Perrimon, Norbert
Formato: Artigo
Idioma:Inglês
Publicado: Cold Spring Harbor Laboratory Press 1998
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC317220/
https://ncbi.nlm.nih.gov/pubmed/9784499
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