Drosophila unpaired encodes a secreted protein that activates the JAK signaling pathway

In vertebrates, many cytokines and growth factors have been identified as activators of the JAK/STAT signaling pathway. In Drosophila, JAK and STAT molecules have been isolated, but no ligands or receptors capable of activating the pathway have been described. We have characterized the unpaired (upd...

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Pubblicato in:	Genes Dev
Autori principali:	Harrison, Douglas A., McCoon, Patricia E., Binari, Richard, Gilman, Michael, Perrimon, Norbert
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Cold Spring Harbor Laboratory Press 1998
Soggetti:	Research Paper
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC317220/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9784499/ https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gad.12.20.3252
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