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Drosophila unpaired encodes a secreted protein that activates the JAK signaling pathway

In vertebrates, many cytokines and growth factors have been identified as activators of the JAK/STAT signaling pathway. In Drosophila, JAK and STAT molecules have been isolated, but no ligands or receptors capable of activating the pathway have been described. We have characterized the unpaired (upd...

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Bibliografiske detaljer
Udgivet i:Genes Dev
Principais autores: Harrison, Douglas A., McCoon, Patricia E., Binari, Richard, Gilman, Michael, Perrimon, Norbert
Format: Artigo
Sprog:Inglês
Udgivet: Cold Spring Harbor Laboratory Press 1998
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC317220/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9784499/
https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gad.12.20.3252
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