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mus304 encodes a novel DNA damage checkpoint protein required during Drosophila development

Checkpoints block cell cycle progression in eukaryotic cells exposed to DNA damaging agents. We show that several Drosophila homologs of checkpoint genes, mei-41, grapes, and 14-3-3ε, regulate a DNA damage checkpoint in the developing eye. We have used this assay to show that the mutagen-sensitive g...

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書誌詳細
主要な著者: Brodsky, Michael H., Sekelsky, Jeff J., Tsang, Garson, Hawley, R. Scott, Rubin, Gerald M.
フォーマット: Artigo
言語:Inglês
出版事項: Cold Spring Harbor Laboratory Press 2000
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オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC316460/
https://ncbi.nlm.nih.gov/pubmed/10733527
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