mus304 encodes a novel DNA damage checkpoint protein required during Drosophila development

Checkpoints block cell cycle progression in eukaryotic cells exposed to DNA damaging agents. We show that several Drosophila homologs of checkpoint genes, mei-41, grapes, and 14-3-3ε, regulate a DNA damage checkpoint in the developing eye. We have used this assay to show that the mutagen-sensitive g...

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Bibliografiske detaljer

Udgivet i:	Genes Dev
Principais autores:	Brodsky, Michael H., Sekelsky, Jeff J., Tsang, Garson, Hawley, R. Scott, Rubin, Gerald M.
Format:	Artigo
Sprog:	Inglês
Udgivet:	Cold Spring Harbor Laboratory Press 2000
Fag:	Research Paper
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC316460/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10733527/
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