Constitutive and Chemokine-dependent Internalization and Recycling of CXCR7 in Breast Cancer Cells to Degrade Chemokine Ligands

CXCR7 is a receptor for chemokines including CXCL12 (SDF-1), a molecule that promotes tumor growth and metastasis in breast cancer and other malignancies. Building upon the recent observation that CXCR7 sequesters CXCL12, we investigated mechanisms for CXCR7-dependent uptake of chemokines. Breast ca...

Full description

Saved in:

Bibliographic Details
Main Authors:	Luker, Kathryn E., Steele, Jessica M., Mihalko, Laura Anne, Ray, Paramita, Luker, Gary D.
Format:	Artigo
Language:	Inglês
Published:	2010
Subjects:	Article
Online Access:	https://ncbi.nlm.nih.gov/pmc/articles/PMC3164491/ https://ncbi.nlm.nih.gov/pubmed/20531309 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2010.212
Tags:	Add Tag No Tags, Be the first to tag this record!

Constitutive and Chemokine-dependent Internalization and Recycling of CXCR7 in Breast Cancer Cells to Degrade Chemokine Ligands

Similar Items