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Allosteric Peptide Regulators of Chemokine Receptors CXCR4 and CXCR7

The chemokine CXCL12 and its shared seven-transmembrane receptors CXCR4 and CXCR7 regulate diseases including cancer, atherosclerosis, autoimmunity, and HIV infection, making these molecules promising drug targets. These molecules also control key processes in normal development and physiology, sugg...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Ehrlich, Anna, Ray, Paramita, Luker, Kathryn E., Lolis, Elias, Luker, Gary D.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3819144/
https://ncbi.nlm.nih.gov/pubmed/23973527
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bcp.2013.08.019
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