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Error-prone nonhomologous end joining repair operates in human pluripotent stem cells during late G2

Genome stability of human embryonic stem cells (hESC) is an important issue because even minor genetic alterations can negatively impact cell functionality and safety. The incorrect repair of DNA double-stranded breaks (DSBs) is the ultimate cause of the formation of chromosomal aberrations. Using G...

詳細記述

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書誌詳細
主要な著者: Bogomazova, Alexandra N., Lagarkova, Maria A., Tskhovrebova, Leyla V., Shutova, Maria V., Kiselev, Sergey L.
フォーマット: Artigo
言語:Inglês
出版事項: Impact Journals LLC 2011
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3164367/
https://ncbi.nlm.nih.gov/pubmed/21685510
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