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UGT1A6 and UGT2B15 Polymorphisms and Acetaminophen Conjugation in Response to a Randomized, Controlled Diet of Select Fruits and Vegetables

Acetaminophen (APAP) glucuronidation is thought to occur mainly by UDP-glucuronosyltransferases (UGT) in the UGT1A family. Interindividual variation in APAP glucuronidation is attributed in part to polymorphisms in UGT1As. However, evidence suggests that UGT2B15 may also be important. We evaluated,...

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Bibliografiske detaljer
Main Authors: Navarro, Sandi L., Chen, Yu, Li, Lin, Li, Shuying S., Chang, Jyh-Lurn, Schwarz, Yvonne, King, Irena B., Potter, John D., Bigler, Jeannette, Lampe, Johanna W.
Format: Artigo
Sprog:Inglês
Udgivet: The American Society for Pharmacology and Experimental Therapeutics 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3164274/
https://ncbi.nlm.nih.gov/pubmed/21666065
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/dmd.111.039149
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