SOD3 Decreases Ischemic Injury Derived Apoptosis through Phosphorylation of Erk1/2, Akt, and FoxO3a

BACKGROUND: Extracellular superoxide dismutase (SOD3), which dismutates superoxide anion to hydrogen peroxide, has been shown to reduce the free radical stress derived apoptosis in tissue injuries. Since both superoxide anion and hydrogen peroxide have a marked impact on signal transduction pathways...

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Bibliografiska uppgifter
Huvudupphovsmän: Laatikainen, Lilja E., Incoronato, Mariarosaria, Castellone, Maria Domenica, Laurila, Juha P., Santoro, Massimo, Laukkanen, Mikko O.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Public Library of Science 2011
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3164207/
https://ncbi.nlm.nih.gov/pubmed/21909393
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0024456
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