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SOD3 Decreases Ischemic Injury Derived Apoptosis through Phosphorylation of Erk1/2, Akt, and FoxO3a

BACKGROUND: Extracellular superoxide dismutase (SOD3), which dismutates superoxide anion to hydrogen peroxide, has been shown to reduce the free radical stress derived apoptosis in tissue injuries. Since both superoxide anion and hydrogen peroxide have a marked impact on signal transduction pathways...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Laatikainen, Lilja E., Incoronato, Mariarosaria, Castellone, Maria Domenica, Laurila, Juha P., Santoro, Massimo, Laukkanen, Mikko O.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3164207/
https://ncbi.nlm.nih.gov/pubmed/21909393
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0024456
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