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SOD3 Decreases Ischemic Injury Derived Apoptosis through Phosphorylation of Erk1/2, Akt, and FoxO3a

BACKGROUND: Extracellular superoxide dismutase (SOD3), which dismutates superoxide anion to hydrogen peroxide, has been shown to reduce the free radical stress derived apoptosis in tissue injuries. Since both superoxide anion and hydrogen peroxide have a marked impact on signal transduction pathways...

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Bibliografiske detaljer
Main Authors: Laatikainen, Lilja E., Incoronato, Mariarosaria, Castellone, Maria Domenica, Laurila, Juha P., Santoro, Massimo, Laukkanen, Mikko O.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3164207/
https://ncbi.nlm.nih.gov/pubmed/21909393
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0024456
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