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SOD3 Decreases Ischemic Injury Derived Apoptosis through Phosphorylation of Erk1/2, Akt, and FoxO3a

BACKGROUND: Extracellular superoxide dismutase (SOD3), which dismutates superoxide anion to hydrogen peroxide, has been shown to reduce the free radical stress derived apoptosis in tissue injuries. Since both superoxide anion and hydrogen peroxide have a marked impact on signal transduction pathways...

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書誌詳細
主要な著者: Laatikainen, Lilja E., Incoronato, Mariarosaria, Castellone, Maria Domenica, Laurila, Juha P., Santoro, Massimo, Laukkanen, Mikko O.
フォーマット: Artigo
言語:Inglês
出版事項: Public Library of Science 2011
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3164207/
https://ncbi.nlm.nih.gov/pubmed/21909393
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0024456
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