Mutations in Drosophila DP and E2F distinguish G(1)–S progression from an associated transcriptional program

The E2F transcription factor, a heterodimer of E2F and DP subunits, is capable of driving the G(1)–S transition of the cell cycle. However, mice in which the E2F-1 gene had been disrupted developed tumors, suggesting a negative role for E2F in controlling cell proliferation in some tissues. The cons...

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Εκδόθηκε σε:	Genes Dev
Κύριοι συγγραφείς:	Royzman, Irena, Whittaker, Allyson J., Orr-Weaver, Terry L.
Μορφή:	Artigo
Γλώσσα:	Inglês
Έκδοση:	Cold Spring Harbor Laboratory Press 1997
Θέματα:	Research Paper
Διαθέσιμο Online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC316409/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9271122/ https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gad.11.15.1999
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